This tip may be useful to avoid other conflicts than the example I give below.
I use Parallels to use Windows. I use Visual Studio, to execute my .NET (C#) program. When I typed Ctrl + F5, it ended up conflicting with the Function keys on the Mac (every time I tried to run, it would try to increase the volume of my speaker—not very helpful).
On the Mac, in the Keyboard settings, I turned on the option "Use the F1-F12 keys to control software features. When this option is selected, press the Fn key to use the F1-F12 keys to control hardware features."
Now, if I really want to change the speaker volume, I press Fn + F5 (or Fn + F4), and Ctrl + F5 within Visual Studio (in Parallels) runs my C# program.